Mirtaz (mirtazapine)
Description
Atypical antidepressant — sedating at lower doses; appetite increase common.
SA brand formulations
| Brand | Generic | Type |
|---|---|---|
| Mirtaz (mirtazapine) | mirtazapine | Atypical antidepressant |
| Remeron (mirtazapine) | mirtazapine | Atypical antidepressant |
SA strengths
15 mg tablet · 30 mg tablet · 45 mg tablet
Typical SA dosing
Often 15–30 mg nocte for depression with insomnia.
Related conditions
- Acute stress reaction
- Adjustment disorder with anxiety
- Adjustment disorder with depressed mood
- Bipolar affective disorder
- Bipolar disorder, current episode depressed
- Burnout / exhaustion disorder (working diagnosis)
- Dysthymic disorder / persistent depressive disorder
- Generalised anxiety disorder
- Major depressive disorder, moderate
- Major depressive disorder, recurrent
- Major depressive disorder, severe
- Major depressive disorder, single episode
- Mixed anxiety and depressive disorder
- Panic disorder
- Post-traumatic stress disorder (PTSD)
- Schizophrenia
References
-
Brand–generic pairings reflect products commonly encountered in SA scripts; confirm current SAHPRA registration on the label or package insert.
SAHPRA; MIMS / SA package inserts -
Strength list shows unit doses commonly available in SA tablets, capsules, inhalers, or injections — verify against the dispensed product.
MIMS / SA package inserts; SA Essential Medicines List (EML); ClaimBuddy curated -
Typical dosing is a general SA prescribing range for claims context only — actual dose must match the treating clinician's script.
MIMS / SA package inserts; ClaimBuddy curated
Data sources
- WHO ICD-10 — Condition names and ICD-10-CM codes in the condition index.
- SAHPRA — South African medicine registration context; brand products must be SAHPRA-registered to be dispensed.
- MIMS / SA package inserts — Registered strengths, formulations, and typical dosing ranges for SA market products.
- SA Essential Medicines List (EML) — Public-sector formulary context for commonly available strengths.
- ClaimBuddy curated — SA brand name collation from intake presets, claim-frequency mapping, and work-impact notes — not a substitute for prescribing information.
Data quality & linkage
| Domain | Records | Completeness | Accuracy | Cross-refs | Linkage | Notes |
|---|---|---|---|---|---|---|
| ICD-10 conditions | 106 | Hand-curated MVP | WHO ICD-10 aligned | Condition↔med rules | WHO API ingest planned | Sync source for Clinical Atlas / Library |
| SA medications | 87 | Curated brands/strengths | SAHPRA/MIMS target | Condition generic maps | Schedule badges linked | SAHPRA register ingest planned |
Official sources & ingest
| Domain | Official source | Feed type | API / access | Refresh | Synced to | Status |
|---|---|---|---|---|---|---|
| Medical Schemes & PMB | Council for Medical Schemes — PMB | HTML / portal | www.medicalschemes.co.za/resources/pmb/ | Daily cache | Library · Clinical Atlas | Ingested |
| Medical Schemes & PMB | CMS Industry Report 2023 | HTML / portal | www.medicalschemes.co.za/media-centre/the… | Annual | Library · Clinical Atlas | Ingested |
| Medical Schemes & PMB | PMB conditions spreadsheet (CMS) | XLSX download | www.medicalschemes.co.za/download/2032/pr… | When CMS updates | Library · Clinical Atlas | Ingested |
| Medical Schemes & PMB | CDL treatment algorithms | HTML / portal | www.medicalschemes.co.za/publications/#20… | When CDL revised | Library · Clinical Atlas | Ingested |
| Clinical Atlas | WHO ICD-10 | HTML / portal | icd.who.int/browse10/2019/en | Per atlas release | Library · Clinical Atlas | Curated / partial API |
| Clinical Atlas | SAHPRA | HTML / portal | www.sahpra.org.za/ | Per atlas release | Library · Clinical Atlas | Curated / partial API |
| Clinical Atlas | MIMS / SA package inserts | Reference | www.mims.co.za/ | Per atlas release | Library · Clinical Atlas | Curated / partial API |
| Clinical Atlas | SA Essential Medicines List (EML) | Reference | www.health.gov.za/ | Per atlas release | Library · Clinical Atlas | Curated / partial API |
| Clinical Atlas | ClaimBuddy curated | Reference | Internal | Per atlas release | Library · Clinical Atlas | Curated / partial API |
| Social security (shared) | ISSA Country Profiles | HTML database | www.issa.int/databases/country-profiles | Two-year regional cycle | Core · Compass ZA | Primary — structure |
| News & conduct | NFOSA press releases | WordPress REST + RSS | nfosa.co.za/wp-json/wp/v2/posts | Hourly cache | Library · compiler | Live — master in Core |
| News & conduct | FSCA media releases | RSS / HTML | www.fsca.co.za/ | Daily | Library news | Planned structured ingest |
| Practitioners | HPCSA i-register | Live HTTP | iregister.hpcsa.co.za/ | 5-min cache | Clinical Atlas · compiler HPCSA lookup | Live proxy |
| Life insurers | NFO Life Insurance Division participants | HTML register | www.nfosa.co.za/participants/life-insuran… | When NFO updates the participant list | Library life-insurers directory · intake autocomplete | Curated — Library directory live |
| Conduct & complaints | NFO Life Insurance Division case reports | HTML case reports | nfosa.co.za/category/case-reports/ | When NFO publishes (curated holdings in Library) | Library language map · wiki · precedent pages | Curated — CR403, CR356, CR351, CR276, CR72, CR259 live in Library |