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Generalised anxiety disorder

F41.1 · Mental health

Clinical summary

Excessive worry about multiple domains for six months or more, with restlessness, fatigue, irritability, muscle tension, or sleep disturbance.

Category context

Conditions affecting mood, anxiety, thinking, or behaviour — insurers still need duty-impact evidence, not diagnosis alone.

Common symptoms

Low mood Anxiety Poor concentration Fatigue Insomnia Panic attacks

Relevant clinicians

Roles commonly involved in assessment and treatment for this condition.

Linked medicines (SA)

Escitalopram

2 brands

SSRI antidepressant for depression and generalised anxiety — generally once-daily dosing.

Brands: Cipralex (escitalopram), Lexamil (escitalopram)

SA strengths: 5 mg tablet · 10 mg tablet · 20 mg tablet

Typical dosing: Often 10 mg mane; may increase to 20 mg daily per response. Elderly: start 5 mg.

Sertraline

2 brands

SSRI used for depression, anxiety, PTSD, and OCD — food does not significantly alter absorption.

Brands: Zoloft (sertraline), Serlife (sertraline)

SA strengths: 50 mg tablet · 100 mg tablet

Typical dosing: Usually start 50 mg daily; common range 50–200 mg daily.

Pregabalin

2 brands

Calcium-channel modulator for neuropathic pain and generalised anxiety — sedation and dizziness common.

Brands: Lyrica (pregabalin), Pregabalin (generic)

SA strengths: 25 mg capsule · 75 mg capsule · 150 mg capsule · 300 mg capsule

Typical dosing: Often titrated 75 mg BD to 150–300 mg BD for pain/anxiety per tolerability.

Alprazolam

1 brand

Short-acting benzodiazepine — dependence risk; insurers query long-term use.

Brands: Xanor (alprazolam)

SA strengths: 0.25 mg tablet · 0.5 mg tablet · 1 mg tablet

Typical dosing: Short courses only; typical 0.25–0.5 mg TDS PRN per strict supervision.

Propranolol

2 brands

Non-selective beta-blocker — used for anxiety somatic symptoms and migraine prevention.

Brands: Propranolol, Inderal (propranolol)

SA strengths: 10 mg tablet · 40 mg tablet · 80 mg tablet

Typical dosing: Anxiety/migraine: commonly 40–80 mg BD; asthma caution.

Prescribed therapy

Session-based referrals — not medicines. Therapy directory

Psychotherapy / CBT

Psychotherapy & counselling

Structured talking therapy (e.g. CBT) for mental health and adjustment.

Session formats: 50 min session · 60 min session

Typical plan: Typically 50–60 min weekly or fortnightly sessions.

Occupational therapy

Occupational therapy

Functional rehabilitation — workplace pacing, ergonomics, ADL retraining.

Session formats: 45 min session · 60 min session

Typical plan: 45–60 min sessions per treating plan.

Therapy references

Data quality & linkage

Core ingest — feeds Library, Clinical Atlas, compiler
Domain Records Completeness Accuracy Cross-refs Linkage Notes
ICD-10 conditions 106 Hand-curated MVP WHO ICD-10 aligned Condition↔med rules WHO API ingest planned Sync source for Clinical Atlas / Library
SA medications 87 Curated brands/strengths SAHPRA/MIMS target Condition generic maps Schedule badges linked SAHPRA register ingest planned

Official sources & ingest

Authority feeds — master ingest in Core ZA (coreza.riskatlas.co.za)
Domain Official source Feed type API / access Refresh Synced to Status
Medical Schemes & PMB Council for Medical Schemes — PMB HTML / portal www.medicalschemes.co.za/resources/pmb/ Daily cache Library · Clinical Atlas Ingested
Medical Schemes & PMB CMS Industry Report 2023 HTML / portal www.medicalschemes.co.za/media-centre/the… Annual Library · Clinical Atlas Ingested
Medical Schemes & PMB PMB conditions spreadsheet (CMS) XLSX download www.medicalschemes.co.za/download/2032/pr… When CMS updates Library · Clinical Atlas Ingested
Medical Schemes & PMB CDL treatment algorithms HTML / portal www.medicalschemes.co.za/publications/#20… When CDL revised Library · Clinical Atlas Ingested
Clinical Atlas WHO ICD-10 HTML / portal icd.who.int/browse10/2019/en Per atlas release Library · Clinical Atlas Curated / partial API
Clinical Atlas SAHPRA HTML / portal www.sahpra.org.za/ Per atlas release Library · Clinical Atlas Curated / partial API
Clinical Atlas MIMS / SA package inserts Reference www.mims.co.za/ Per atlas release Library · Clinical Atlas Curated / partial API
Clinical Atlas SA Essential Medicines List (EML) Reference www.health.gov.za/ Per atlas release Library · Clinical Atlas Curated / partial API
Clinical Atlas ClaimBuddy curated Reference Internal Per atlas release Library · Clinical Atlas Curated / partial API
Social security (shared) ISSA Country Profiles HTML database www.issa.int/databases/country-profiles Two-year regional cycle Core · Compass ZA Primary — structure
News & conduct NFOSA press releases WordPress REST + RSS nfosa.co.za/wp-json/wp/v2/posts Hourly cache Library · compiler Live — master in Core
News & conduct FSCA media releases RSS / HTML www.fsca.co.za/ Daily Library news Planned structured ingest
Practitioners HPCSA i-register Live HTTP iregister.hpcsa.co.za/ 5-min cache Clinical Atlas · compiler HPCSA lookup Live proxy
Life insurers NFO Life Insurance Division participants HTML register www.nfosa.co.za/participants/life-insuran… When NFO updates the participant list Library life-insurers directory · intake autocomplete Curated — Library directory live
Conduct & complaints NFO Life Insurance Division case reports HTML case reports nfosa.co.za/category/case-reports/ When NFO publishes (curated holdings in Library) Library language map · wiki · precedent pages Curated — CR403, CR356, CR351, CR276, CR72, CR259 live in Library

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