Chronic fatigue syndrome / ME

G93.3 · Other

Clinical summary

Profound fatigue, post-exertional worsening, and cognitive symptoms not fully explained by other conditions.

Category context

Symptom-based or non-specific codes — pair with functional impact in your story.

Common symptoms

Fatigue Malaise Reduced stamina

Relevant clinicians

Roles commonly involved in assessment and treatment for this condition.

Physician (specialist) Medical doctor Internal medicine specialist — often manages complex or multi-system conditions. Psychiatrist Mental health Medical doctor specialising in mental illness — can diagnose, prescribe, and admit. Occupational Therapist Allied health Assesses daily and work functioning — ADLs and return-to-work capacity. Independent Medical Examiner (IME) Assessor Assessor Insurer- or employer-appointed assessor — not treating doctor. General Practitioner (GP) Medical doctor Primary care doctor — first point for sick notes, referrals, and ongoing treatment.

Linked medicines (SA)

Amitriptyline

4 brands

Tricyclic antidepressant — low doses often used for nerve pain, migraine prevention, or sleep.

Brands: Amitriptyline, Trepiline (amitriptyline), Trepiline (low-dose amitriptyline), Elavil (amitriptyline)

SA strengths: 10 mg tablet · 25 mg tablet · 50 mg tablet

Typical dosing: Pain/sleep: 10–25 mg nocte; depression: higher divided doses under supervision.

Pregabalin

2 brands

Calcium-channel modulator for neuropathic pain and generalised anxiety — sedation and dizziness common.

Brands: Lyrica (pregabalin), Pregabalin (generic)

SA strengths: 25 mg capsule · 75 mg capsule · 150 mg capsule · 300 mg capsule

Typical dosing: Often titrated 75 mg BD to 150–300 mg BD for pain/anxiety per tolerability.

Prescribed therapy

Session-based referrals — not medicines. Therapy directory

Occupational therapy

Functional rehabilitation — workplace pacing, ergonomics, ADL retraining.

Session formats: 45 min session · 60 min session

Typical plan: 45–60 min sessions per treating plan.

Physiotherapy (prescribed)

Physiotherapy

Prescribed rehabilitation for pain, injury, and mobility restoration.

Session formats: 30 min session · 45 min session · 60 min session

Typical plan: Usually 30–60 min sessions weekly to thrice weekly per referral.

Therapy references

ME/CFS — activity management — NICE NG206 (fatigue syndromes)
Graded activity only where appropriate; crash patterns must be linked to material duties in claim narrative.
Source ↗
Occupational therapy — work capacity — ClaimBuddy curated / HPCSA OT scope
ADL and workplace pacing assessments; pairs with material-duty mapping in functional capacity evidence.
Independent medical examination (IME) context — ClaimBuddy curated
Assessor is not your treating doctor — prepare material duties, chronology, and treating specialist reports separately.

Data quality & linkage

Core ingest — feeds Library, Clinical Atlas, compiler

Domain	Records	Completeness	Accuracy	Cross-refs	Linkage	Notes
ICD-10 conditions	106	Hand-curated MVP	WHO ICD-10 aligned	Condition↔med rules	WHO API ingest planned	Sync source for Clinical Atlas / Library
SA medications	87	Curated brands/strengths	SAHPRA/MIMS target	Condition generic maps	Schedule badges linked	SAHPRA register ingest planned

Official sources & ingest

Authority feeds — master ingest in Core ZA (coreza.riskatlas.co.za)

Domain	Official source	Feed type	API / access	Refresh	Synced to	Status
Medical Schemes & PMB	Council for Medical Schemes — PMB	HTML / portal	www.medicalschemes.co.za/resources/pmb/	Daily cache	Library · Clinical Atlas	Ingested
Medical Schemes & PMB	CMS Industry Report 2023	HTML / portal	www.medicalschemes.co.za/media-centre/the…	Annual	Library · Clinical Atlas	Ingested
Medical Schemes & PMB	PMB conditions spreadsheet (CMS)	XLSX download	www.medicalschemes.co.za/download/2032/pr…	When CMS updates	Library · Clinical Atlas	Ingested
Medical Schemes & PMB	CDL treatment algorithms	HTML / portal	www.medicalschemes.co.za/publications/#20…	When CDL revised	Library · Clinical Atlas	Ingested
Clinical Atlas	WHO ICD-10	HTML / portal	icd.who.int/browse10/2019/en	Per atlas release	Library · Clinical Atlas	Curated / partial API
Clinical Atlas	SAHPRA	HTML / portal	www.sahpra.org.za/	Per atlas release	Library · Clinical Atlas	Curated / partial API
Clinical Atlas	MIMS / SA package inserts	Reference	www.mims.co.za/	Per atlas release	Library · Clinical Atlas	Curated / partial API
Clinical Atlas	SA Essential Medicines List (EML)	Reference	www.health.gov.za/	Per atlas release	Library · Clinical Atlas	Curated / partial API
Clinical Atlas	ClaimBuddy curated	Reference	Internal	Per atlas release	Library · Clinical Atlas	Curated / partial API
Social security (shared)	ISSA Country Profiles	HTML database	www.issa.int/databases/country-profiles	Two-year regional cycle	Core · Compass ZA	Primary — structure
News & conduct	NFOSA press releases	WordPress REST + RSS	nfosa.co.za/wp-json/wp/v2/posts	Hourly cache	Library · compiler	Live — master in Core
News & conduct	FSCA media releases	RSS / HTML	www.fsca.co.za/	Daily	Library news	Planned structured ingest
Practitioners	HPCSA i-register	Live HTTP	iregister.hpcsa.co.za/	5-min cache	Clinical Atlas · compiler HPCSA lookup	Live proxy
Life insurers	NFO Life Insurance Division participants	HTML register	www.nfosa.co.za/participants/life-insuran…	When NFO updates the participant list	Library life-insurers directory · intake autocomplete	Curated — Library directory live
Conduct & complaints	NFO Life Insurance Division case reports	HTML case reports	nfosa.co.za/category/case-reports/	When NFO publishes (curated holdings in Library)	Library language map · wiki · precedent pages	Curated — CR403, CR356, CR351, CR276, CR72, CR259 live in Library

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